BONE TRIVIA

Did you know your skeleton is renewed every 7-10 years completely?
Bone is continuously remodeling itself.  Bone is a metabolically active tissue. Bone remodeling is a coupled response of formation and resorption.

 

Did you know that bone formation can be monitored using blood tests?
These are the tests: Osteocalcin, Bone Specific Alkaline Phosphatase, P1NP


Did you know the bone resorption can be monitored using blood and urine tests?
These are the tests Serum C-Telopeptide and 2nd AM Urine for N-Telopeptide


Did you know how much Calcium you are losing can be measured in the urine?
It is measured by a 24 hour urine collection for total Calcium and creatinine clearance.
Using the results of this test can help the physician know how much calcium you need.


Did you know how much Calcium your absorbing with food and supplements?
If you are taking Calcium supplements and you have a Vitamin D deficiency you will not absorb the supplements. Vitamin D levels affect your calcium absorption.


Did you know that Vitamin D levels can be measured in the blood?
These are blood tests for Vitamin D:

Vitamin D, 1,25-Dihydroxy

Vitamin D, 25-Hydroxy


Did you know that some drugs can cause bone loss?
These are some drugs that may cause bone loss.

  • Aluminum-containing antacids
  • Antiseizure medicines (only some) such as Dilantin® or Phenobarbital
  • Aromatase inhibitors such as Arimidex®, Aromasin® and Femara®
  • Cancer chemotherapeutic drugs
  • Cyclosporine A and FK506 (Tacrolimus)
  • Gonadotropin releasing hormone (GnRH) such as Lupron® and Zoladex®
  • Heparin
  • Lithium
  • Medroxyprogesterone acetate for contraception (Depo-Provera®)
  • Methotrexate
  • Proton pump inhibitors (PPIs) such as Nexium®, Prevacid® and Prilosec®
  • Selective serotonin reuptake inhibitors (SSRIs) such as Lexapro®, Prozac® and Zoloft®
  • Steroids (glucocorticoids) such as cortisone and prednisone
  • Tamoxifen® (premenopausal use)
  • Thiazolidinediones such as Actos® and Avandia®
  • Thyroid hormones in excess

Note: This list may not include all drugs that may cause bone loss.

If a medication is required that causes loss of bone. Bone density testing can be indicated and the above lab tests can help in monitoring the effect of such drugs on your bones. You can ask your physician if a bone density testing is needed,  then you can contact us directly with your Physician’s order.

A good resource for Medicines that May Cause Bone Loss is the National Osteoporosis Foundation.


Did you know that Vitamin D is essential for Calcium absorption?
Vitamin D and Magnesium are necessary to help convert calcium in food and supplements to a form your body can use.  Check your calcium supplement; does it have vitamin d and magnesium?  While it’s more convenient to have them together, it’s not absolutely necessary if you are already taking a vitamin d supplement, along with a multivitamin containing magnesium.  But it doesn’t hurt!

Here’s something you may not realize when it comes to calcium.  At best, the body can use 40% of what you take in via food.  And supplements tend to be worse; anywhere from negligible to around 25%. Why?  Because the Calcium in food is more bio-available.

Also consider this; calcium uptake starts in the stomach, where it’s broken apart by stomach acids.  If your calcium supplement isn’t being digested by your stomach acids, then it’s just passing through your body and on its way out.

Here’s an easy way to tell if your calcium supplement is letting you down or not.  Take a half-cup of vinegar and drop a serving (however many tablets that is) into the vinegar.  Walk away and come back 20 minutes later.  If your supplement is still recognizable as what you put in, your body can’t use it.  If it’s dissolved, your body can start the uptake.